- 학력 및 경력
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[학력]
- Doctor of Engineering in Biological Information, Tokyo Institute of Technology, Tokyo, Japan
- Master of Science in Biological Information, Tokyo Institute of Technology, Tokyo, Japan
- Bachelor of Science in Biotechnology, Tokyo Institute of Technology, Tokyo, Japan
- 한-일정부 이공계학부유학 프로그램
[경력]
- (현) 국제뇌교육종합대학원대학교 통합헬스케어학과/융합생명과학과 교수
- (현) 한국뇌과학연구원 부원장
- (전) Researcher, Weizmann Institute of Science, Rehovot, Israel
- (전) 박사후연구원, Weizmann Institute of Science, Rehovot, Israel
- 논문
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- Mijan MA, Kim JY, Moon SY, Choi SH, Nah SY, Yang HJ (2019) Gintonin Enhances Proliferation, Late Stage Differentiation, and Cell Survival From Endoplasmic Reticulum Stress of Oligodendrocyte Lineage Cells. Frontiers in Pharmacology. 10:1211.
- Kim JY, Yoon JY, Sugiura Y, Lee SK, Park JD, Song GJ, Yang HJ. (2019) Dendropanax morbiferus leaf extract facilitates oligodendrocyte development. R. Soc. open sci. 6:190266.
- Lee SH, Hwang SM, Kang DH, Yang HJ. (2019) Brain education-based meditation for patients with hypertension and/or type 2 diabetes A pilot randomized controlled trial. Medicine. 98(19):e15574.
- Bang ML, Vainshtein A, Yang HJ, Eshed-Eisenbach Y, Devaux J, Werner HB, Peles E (2018) Glial M6B stabilizes the axonal membrane at peripheral nodes of Ranvier.Glia. 66:801–812.
- Konno A, Ikegami K, Konish Y, Yang HJ, Abe M, Yamazaki M, Sakimura K, Yao I, Shiba K, Inaba K, Setou M (2016). Doublet 7 shortening, doublet 5-preferential poly-Glu reduction, and beating stall of sperm flagella in Ttll9-/- mice. Journal of Cell Science, 185983.
- Yang HJ, Vainshtein A, Maik-Rachline G, Peles E (2016). G protein coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination. Nat. Commun. 7:10884-108890.
- Onishi S, Tatsumi Y, Wada K, Yang HJ, Sugiura Y, Setou M, Yoshikawa H (2013) “Sulfatide accumulation in the dystrophic terminals of gracile axonal dystrophy mice: lipid analysis using matrix-assisted laser desorption/ionization imaging mass spectrometry.” Med Mol Morphol. 46(3):160-5.
- Yang HJ, Sugiura Y, Ikegami K, Konishi Y, Setou M (2012). “Axonal gradient of arachidonic acid-containing phosphatidylcholine and its dependence on actin dynamics” J Biol Chem 287(8):5290-300.
- Yang HJ, Ishizaki I, Sanada N, Zaima N, Sugiura Y, Yao I, Ikegami K, Setou M (2010). “Detection of characteristic distributions of phospholipids head groups and fatty acids on neurite surface by time of flight-secondary ion mass spectrometry” Medical Molecular Morphology 43(3):158-64.
- Yang HJ, Sugiura Y, Ishizaki I, Sanada N, Ikegami K, Zaima N, Shrivas K, Setou M (2010). “Imaging of lipids in cultured mammalian neurons by matrix assisted laser/desorption ionization and secondary ion mass spectrometry” Surface and Interface Analysis 42 (10): 1606-1611.
- Yang HJ, Sugiura Y, Ikegami K, Setou M (2010). “Imaging of Cultured Cells by Mass Spectrometry.” Imaging Mass Spectrometry, Ed. Setou M, Springer-Verlag. pp 159-168 (Textbook. English Version).
- Setou M, Shrivas K, Sroyraya M, Yang HJ, Sugiura Y, Moribe J, Kondo A, Tsutsumi K, Kimura Y, Kurabe N, Hayasaka T, Goto-Inoue N, Zaima N, Ikegami K, Sobhon P, Konishi Y (2010) “Development and applications of mass microscopy” Medical Molecular Morphology 43(1):1-5. Review.
- Yang HJ, Takagi H, Konishi Y, Ageta H, Ikegami K, Yao I, Sato S, Hatanaka K, Inoguchi K, Seog D, Setou M (2008). ‘’Transmembrane and Ubiquitin-Like Domain-Containing Protein 1(Tmub1/HOPS) Facilitates Surface Expression of GluR2-Containing AMPA Receptors.” PLoS one 3(7):e2809.
- Yang HJ, Sugiura Y, Ikegami K, Setou M (2008). “Imaging of Cultured Cells by Mass Spectrometry” Imaging Mass Spectrometry, Ed. M. Setou, Springer-Verlag. pp 95-101 (Textbook. Japanese Version).
- Setou M, Matsumoto M, Yang HJ (2006). Receptor transport by motor proteins. Seikagaku 78(6):512-6.
- 특허
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- US Provisional patent application in entitled: “Method for modulating myelination”. Serial no. 62/304,242
- 학회/세미나
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- Yang HJ, Vainshtein A, Galia Maik-Rachline, Peles E (2016) “G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination” Oral presentation. Glia in Health & Disease meeting, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
- Yang HJ, Vainshtein A, Peles E (2015) “Negative regulation of oligodendrocyte differentiation and myelination” Oral presentation. Molecular Neuroscience Forum seminar, Weizmann Institute of Science, Israel.
- Yang HJ, Peles E (2014) “A role of G protein-coupled receptor for the intrinsic homeostasis of oligodendrocytes” Oral presentation. Department of Molecular Cell Biology Seminar, Weizmann Institute of Science, Israel.
- Yang HJ, Peles E (2013) “G protein-coupled receptors in myelination” Oral presentation. Department of Molecular Cell Biology Seminar, Weizmann Institute of Science, Israel.
- Yang HJ, Peles E (2011) “G protein-coupled receptors in CNS myelination” Present at 10th Biennial ISN satellite meeting on Myelin Biology, Kolymvari, Crete.
- Yang HJ, Sugiura Y, Ikegami K, Konishi Y, Setou M (2010) “Axonal gradient of phosphatidylcholines in neurons“ Present at the 62th meeting of the Japan Society for Cell Biology, Osaka, Japan.
- Yang HJ, Sugiura Y, Setou M (2010) “The analysis of the phospholipid distribution in neurons using imaging mass spectrometry” The research achievements of GCOE Program, Yokohama, Japan.
- Yang HJ, Sugiura Y, Ishizaki I, Sanada N, Ikegami K, Zaima N, Setou M (2009) “Secondary ion mass spectrometry of biomedical samples” Present at the 7th meeting of Atomic Level Characterization, December in Hawaii, USA.
- Yang HJ, Sugiura Y, Konishi Y, Ikegami K, Setou M (2009) “The analysis of the phospholipid distribution in neurons using imaging mass spectrometry” Present at the 39th annual meeting of the Society for Neuroscience , Chicago, U.S.A.
- Yang HJ, Setou M, (2009). “Development and application of high resolution imaging mass spectrometry” Oral presentation. Presented at the 9th meeting of Hamamatsu-Kyungpook Joint Medical Symposium, Daegu, Republic of Korea.
- Yang HJ, Sugiura Y, Ikegami K, Yamada M, Konishi Y, Setou M (2008). “Analysis of lipid composition in axon undergoing Wallerian degeneration using imaging mass spectrometry.” Paper presented at the 38th annual meeting of the Society for Neuroscience, Washington, U.S.A.
- Setou M, Yang HJ, Sugiura Y (2008). “Mass Microscopic Analysis revealed the dynamic Property of Plasma Membrane Lipids Component” Paper presented at the 9th Asia-Pacific Microscopy Conference, Jeju, Republic of Korea.
- Ishizaki I, Sanada N, Miyayama T, Iida S, Yang HJ, Zaima N, Sugiura Y, Setou M. (2008). “Mass Imaging of Rough Cell Surfaces by TOF-SIMS” Paper presented at the 4th Chinese Conference on Secondary Ion Mass Spectrometry, Beijing, China
- Yang HJ, Takagi H, Setou M (2007). “HOPS contributes to surface expression of GluR2-containing AMPAR.” Paper presented at the 37th annual meeting of the Society for Neuroscience, San Diego, U.S.A.
- Yang HJ, Takagi H, Hatanaka K, Setou M (2006). “GluR2 dynamics depending on a ubiquitin-like protein, HOPS.” Paper presented at the 36th annual meeting of the Society for Neuroscience, Atlanta, U.S.A.
- Yang HJ, Takagi H, Hatanaka K, Setou M (2006). “HOPS regulates AMPA receptor trafficking via GRIP1 binding.” Paper presented at the 29th annual meeting of the Japan Neuroscience Society, Kyoto, Japan
