학과소개미래를 선도할 인성과 창의성을 갖춘 전문가 양성

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학력 및 경력
    [학력]
  • Doctor of Engineering in Biological Information, Tokyo Institute of Technology, Tokyo, Japan
  • Master of Science in Biological Information, Tokyo Institute of Technology, Tokyo, Japan
  • Bachelor of Science in Biotechnology, Tokyo Institute of Technology, Tokyo, Japan
  • 한-일정부 이공계학부유학 프로그램
    • [경력]
  • (현) 국제뇌교육종합대학원대학교 통합헬스케어학과/융합생명과학과 교수
  • (현) 한국뇌과학연구원 부원장
  • (전) Researcher, Weizmann Institute of Science, Rehovot, Israel
  • (전) 박사후연구원, Weizmann Institute of Science, Rehovot, Israel
논문
  • Yang HJ, Koh E, Sugn MK, Kang HJ (2021) Changes Induced by Mind–Body Intervention Including Epigenetic Marks and Its Effects on Diabetes. International Journal of Molecular Sciences. 28;22(3):1317
  • Sung MK, Ha NH, Lee US, and Yang HJ (2020) A cross-sectional study on the relationship between meditation training and emotional intelligence in women. Nursing open.  https://doi.org/10.1002/nop2.715
  • Kang HJ, An SC, Kim NO, Sung MK, Kang YJ, Lee US and Yang HJ (2020) Meditative Movement Affects Working Memory Related to Neural Activity in Adolescents: A Randomized Controlled Trial. Frontiers in Psychology. 11:931.
  • Sung MK, Lee US, Ha NH, Koh E and Yang HJ (2020) A potential association of meditation with menopausal symptoms and blood chemistry in healthy women: a pilot cross-sectional study. Medicine. 99(36)e22048.
  • Mijan MA, Kim JY, Moon SY, Choi SH, Nah SY, Yang HJ (2019) Gintonin Enhances Proliferation, Late Stage Differentiation, and Cell Survival From Endoplasmic Reticulum Stress of Oligodendrocyte Lineage Cells. Frontiers in Pharmacology. 10:1211.
  • Kim JY, Yoon JY, Sugiura Y, Lee SK, Park JD, Song GJ, Yang HJ. (2019) Dendropanax morbiferus leaf extract facilitates oligodendrocyte development. R. Soc. open sci. 6:190266.
  • Lee SH, Hwang SM, Kang DH, Yang HJ. (2019) Brain education-based meditation for patients with hypertension and/or type 2 diabetes A pilot randomized controlled trial. Medicine. 98(19):e15574.
  • Bang ML, Vainshtein A, Yang HJ, Eshed-Eisenbach Y, Devaux J, Werner HB, Peles E (2018) Glial M6B stabilizes the axonal membrane at peripheral nodes of Ranvier.Glia. 66:801–812.
  • Konno A, Ikegami K, Konish Y, Yang HJ, Abe M, Yamazaki M, Sakimura K, Yao I, Shiba K, Inaba K, Setou M (2016). Doublet 7 shortening, doublet 5-preferential poly-Glu reduction, and beating stall of sperm flagella in Ttll9-/- mice. Journal of Cell Science, 185983.
  • Yang HJ, Vainshtein A, Maik-Rachline G, Peles E (2016). G protein coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination. Nat. Commun. 7:10884-108890.
  • Onishi S, Tatsumi Y, Wada K, Yang HJ, Sugiura Y, Setou M, Yoshikawa H (2013) “Sulfatide accumulation in the dystrophic terminals of gracile axonal dystrophy mice: lipid analysis using matrix-assisted laser desorption/ionization imaging mass spectrometry.” Med Mol Morphol. 46(3):160-5.
  • Yang HJ, Sugiura Y, Ikegami K, Konishi Y, Setou M (2012). “Axonal gradient of arachidonic acid-containing phosphatidylcholine and its dependence on actin dynamics” J Biol Chem 287(8):5290-300.
  • Yang HJ, Ishizaki I, Sanada N, Zaima N, Sugiura Y, Yao I, Ikegami K, Setou M (2010). “Detection of characteristic distributions of phospholipids head groups and fatty acids on neurite surface by time of flight-secondary ion mass spectrometry” Medical Molecular Morphology 43(3):158-64.
  • Yang HJ, Sugiura Y, Ishizaki I, Sanada N, Ikegami K, Zaima N, Shrivas K, Setou M (2010). “Imaging of lipids in cultured mammalian neurons by matrix assisted laser/desorption ionization and secondary ion mass spectrometry” Surface and Interface Analysis 42 (10): 1606-1611.
  • Yang HJ, Sugiura Y, Ikegami K, Setou M (2010). “Imaging of Cultured Cells by Mass Spectrometry.” Imaging Mass Spectrometry, Ed. Setou M, Springer-Verlag. pp 159-168 (Textbook. English Version).
  • Setou M, Shrivas K, Sroyraya M, Yang HJ, Sugiura Y, Moribe J, Kondo A, Tsutsumi K, Kimura Y, Kurabe N, Hayasaka T, Goto-Inoue N, Zaima N, Ikegami K, Sobhon P, Konishi Y (2010) “Development and applications of mass microscopy” Medical Molecular Morphology 43(1):1-5. Review.
  • Yang HJ, Takagi H, Konishi Y, Ageta H, Ikegami K, Yao I, Sato S, Hatanaka K, Inoguchi K, Seog D, Setou M (2008). ‘’Transmembrane and Ubiquitin-Like Domain-Containing Protein 1(Tmub1/HOPS) Facilitates Surface Expression of GluR2-Containing AMPA Receptors.” PLoS one 3(7):e2809.
  • Yang HJ, Sugiura Y, Ikegami K, Setou M (2008). “Imaging of Cultured Cells by Mass Spectrometry” Imaging Mass Spectrometry, Ed. M. Setou, Springer-Verlag. pp 95-101 (Textbook. Japanese Version).
  • Setou M, Matsumoto M, Yang HJ (2006). Receptor transport by motor proteins. Seikagaku 78(6):512-6.
특허
  • 황칠나무 추출물을 포함하는 탈수초 질환의 예방 또는 치료용 조성물 (Serial No. 10-2216752)
  • 진토닌을 포함하는 희소돌기아교세포 분화용 조성물 및 탈수초성 질환의 예방 또는 치료용 조성물 (Serial No. 10-2316236)
  • US Provisional patent application in entitled: “Method for modulating myelination”. Serial no. 62/304,242
학회/세미나
  • Yang HJ, Vainshtein A, Galia Maik-Rachline, Peles E (2016) “G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination” Oral presentation. Glia in Health & Disease meeting, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
  • Yang HJ, Vainshtein A, Peles E (2015) “Negative regulation of oligodendrocyte differentiation and myelination” Oral presentation. Molecular Neuroscience Forum seminar, Weizmann Institute of Science, Israel.
  • Yang HJ, Peles E (2014) “A role of G protein-coupled receptor for the intrinsic homeostasis of oligodendrocytes” Oral presentation. Department of Molecular Cell Biology Seminar, Weizmann Institute of Science, Israel.
  • Yang HJ, Peles E (2013) “G protein-coupled receptors in myelination” Oral presentation. Department of Molecular Cell Biology Seminar, Weizmann Institute of Science, Israel.
  • Yang HJ, Peles E (2011) “G protein-coupled receptors in CNS myelination” Present at 10th Biennial ISN satellite meeting on Myelin Biology, Kolymvari, Crete.
  • Yang HJ, Sugiura Y, Ikegami K, Konishi Y, Setou M (2010) “Axonal gradient of phosphatidylcholines in neurons“ Present at the 62th meeting of the Japan Society for Cell Biology, Osaka, Japan.
  • Yang HJ, Sugiura Y, Setou M (2010) “The analysis of the phospholipid distribution in neurons using imaging mass spectrometry” The research achievements of GCOE Program, Yokohama, Japan.
  • Yang HJ, Sugiura Y, Ishizaki I, Sanada N, Ikegami K, Zaima N, Setou M (2009) “Secondary ion mass spectrometry of biomedical samples” Present at the 7th meeting of Atomic Level Characterization, December in Hawaii, USA.
  • Yang HJ, Sugiura Y, Konishi Y, Ikegami K, Setou M (2009) “The analysis of the phospholipid distribution in neurons using imaging mass spectrometry” Present at the 39th annual meeting of the Society for Neuroscience , Chicago, U.S.A.
  • Yang HJ, Setou M, (2009). “Development and application of high resolution imaging mass spectrometry” Oral presentation. Presented at the 9th meeting of Hamamatsu-Kyungpook Joint Medical Symposium, Daegu, Republic of Korea.
  • Yang HJ, Sugiura Y, Ikegami K, Yamada M, Konishi Y, Setou M (2008). “Analysis of lipid composition in axon undergoing Wallerian degeneration using imaging mass spectrometry.” Paper presented at the 38th annual meeting of the Society for Neuroscience, Washington, U.S.A.
  • Setou M, Yang HJ, Sugiura Y (2008). “Mass Microscopic Analysis revealed the dynamic Property of Plasma Membrane Lipids Component” Paper presented at the 9th Asia-Pacific Microscopy Conference, Jeju, Republic of Korea.
  • Ishizaki I, Sanada N, Miyayama T, Iida S, Yang HJ, Zaima N, Sugiura Y, Setou M. (2008). “Mass Imaging of Rough Cell Surfaces by TOF-SIMS” Paper presented at the 4th Chinese Conference on Secondary Ion Mass Spectrometry, Beijing, China
  • Yang HJ, Takagi H, Setou M (2007). “HOPS contributes to surface expression of GluR2-containing AMPAR.” Paper presented at the 37th annual meeting of the Society for Neuroscience, San Diego, U.S.A.
  • Yang HJ, Takagi H, Hatanaka K, Setou M (2006). “GluR2 dynamics depending on a ubiquitin-like protein, HOPS.” Paper presented at the 36th annual meeting of the Society for Neuroscience, Atlanta, U.S.A.
  • Yang HJ, Takagi H, Hatanaka K, Setou M (2006). “HOPS regulates AMPA receptor trafficking via GRIP1 binding.” Paper presented at the 29th annual meeting of the Japan Neuroscience Society, Kyoto, Japan
연구주제
  • 스트레스와 스트레스 관리를 주제로 다음과 같은 연구를 진행하고 있습니다.
임상연구
  • 심리적 스트레스와 그것을 관리하는 방법 (예. 명상 등)이 인체에 미치는 효과에 대해 분자생물학적인 방법을 사용하여 연구하고 있습니다. 이와 더불어, 인문사회학적 방법, 뇌파 등 생체신호 측정방법을 활용하여 다학제간 연구도 수행하고 있습니다. 인체에 미치는 효과에 있어서는, 신체 (증상)에서의 변화 (노화, 염증, 수면, 통증 등), 정서에서의 변화 (불안, 우울 등), 인지에서의 변화 (작업기억 등), 사회성, 자아존중감 등 다양한 관점에서 연구를 진행하고 있습니다.
메커니즘 연구
  • 스트레스와 스트레스 관리가 미치는 건강에의 영향에 대한 메커니즘을 이해하기 위해 다양한 모델을 사용하여 뇌-말초(장, 근육, 간, 지방조직 등)의 연결 변화에 대한 연구를 수행하고 있습니다. 또한, 황칠, 인삼 등 다양한 천연물과 천연물 유래의 유효물질들이 이러한 스트레스 (관리)에 의해 변화하는 뇌-말초 축에 어떤 영향을 미치며 식품이나 약물로서의 개발가능성에 대해서도 연구를 진행하고 있습니다.
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